Understanding what signals mediate motor neuron and muscle communication is essential for exploring new treatments for muscle-related and neurological diseases, such as amyotrophic lateral sclerosis (ALS). In the current study, researchers at Karolinska Institutet wanted to know how a muscle-produced protein called neurturin affects neuromuscular function. For that reason, researchers are looking for molecules that can by themselves bring about some of the benefits of physical exercise. However, for some patients with debilitating diseases, exercise is not always possible. Muscle health is a major determinant of overall health and the best way to keep muscles healthy is to exercise regularly.
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